Adequacy of peritoneal dialysis and the importance of preserving residual renal function

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Adequacy of peritoneal dialysis and the importance of preserving residual renal function.

The well-being and survival of dialysis patients not only depend on the removal of waste products and excess fluid, but also on the prevention of cardiovascular complications by maintaining normovolaemia and adequate blood pressure and avoidance of ectopic calcification. Also, the maintenance of nutritional status and adequate removal of middle molecules are amongst the most important issues in...

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The importance of residual renal function in peritoneal dialysis patients.

Increased peritoneal clearance can compensate for reductions in renal solute removal in patients receiving peritoneal dialysis (PD); however there is abundant evidence to suggest that renal rather than peritoneal clearance contributes to clinical outcomes. We review the evidence investigating the impact of residual renal function (RRF) and peritoneal solute clearances on survival and quality of...

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Strategies for preserving residual renal function in peritoneal dialysis patients

Although there have been many advancements in the treatment of patients with chronic kidney disease (CKD) over the last 50 years, in terms of reducing cardiovascular risk, mortality remains unacceptably high, particularly for those patients who progress to stage 5 CKD and initiate dialysis (CKD5d). As mortality risk increases exponentially with progressive CKD stage, the question arises as to w...

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Preserving residual renal function in peritoneal dialysis: volume or biocompatibility?

3. Liu S, Quarles LD. How fibroblast growth factor 23 works. J Am Soc Nephrol 2007; 18: 1637–1647 4. Jean G, Terrat JC, Vanel T et al. High levels of serum Fibroblast Growth Factors (FGF)-23 are associated with increased mortality in long haemodialysis patients. Nephrol Dial Transplant 2009; 24: 2792– 2796 5. Gutiérrez OM, Mannstadt M, Isakova T et al. Fibroblast growth factor 23 and mortality ...

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Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study.

Studies of the adequacy of peritoneal dialysis and recommendations have assumed that renal and peritoneal clearances are comparable and therefore additive. The CANUSA data were reanalyzed in an effort to address this assumption. Among the 680 patients in the original CANUSA study, 601 had all of the variables of interest for this report. Adequacy of dialysis was estimated from GFR (mean of rena...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2006

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/gfl188